Department of Entomology


Brian Federiciucr entomology

Distinguished Professor of Entomology
Location: Entomology 324
(951) 827-5006


Research Specialization - As an insect pathologist, the research in my laboratory focuses on (1) understanding the basic microbiology of pathogens that attack insects, and (2) the use of this knowledge to develop pathogens or their products to control insect pests. Currently, our major emphasis is on the bacterium, Bacillus thuringiensis. We are studying the molecular biology of insecticidal protein synthesis in this bacterium, and developing a variety of protein combinations for insect control to be used as bacterial insecticides or to construct insecticidal transgenic plants. These new types of control agents are more environmentally friendly than synthetic chemical insecticides. In addition to our studies on B. thuringiensis, we also have studies underway on insect baculoviruses and ascoviruses. The baculovirus studies are directed toward understanding baculovirus pathology, and then using this knowledge to make better recombinant baculovirus insecticides. Ascoviruses compose a newly discovered family of large double-stranded DNA viruses that attack lepidopteran insects. Our studies of this group are aimed at understanding their phylogenetic origin, pathogenesis, and molecular biology.


BS Animal Science 1966
Rutgers University
MS Medical Entomology 1967
University of Florida
PhD Medical Entomology/Insect Pathology 1970
University of Florida


2008 Entomological Society of America, C.W. Woodworth Award
2005 Academic Senate Faculty Research Lecturer Award
2004 Founder's Lecturer Award, Society for Invertebrate Pathology
2003 USDA Secretary's Individual Honor Award for Superior Service
1997 Elected Fellow, American Association for the Advancement of Science
1991 Entomological Society of America, National Distinguished Teaching Award
1983, 1990, 1991 Entomological Society of America, Pacific Branch, Distinguished Teaching Award:

Research Area

Insect pathology and microbial control with emphasis on viral and bacterial pathogens of medically or agriculturally important insects. Not taking students at this time.


Recent Publications

Diaz-Mendoza, M., D. K. Bideshi, and B. A. Federici. 2012. A 54-kDa protein encoded by pBtoxis is required for parasporal body structural integrity in Bacillus thuringiensis subsp. israelensis. Journal of Bacteriology. In press.


Barboza-Corona, J. E., H.-W. Park, D. K. Bideshi, and B. A. Federici. 2012. The 60-kDa protein encoded by orf2 in the cry19A operon of Bacillus thuringiensis subsp. jegathesan functions like a C-terminal crystallization domain. Applied and Environmental Microbiology. In press.


Diaz-Mendoza, M., D. K. Bideshi, F. Ortego, G. F. Farinos, and B. A. Federici. 2012. The 20-kDa chaperone-like protein of Bacillus thuringiensis spp. israelensis enhances yield, crystal size and solubility of Cry3A. Letters in Applied Microbiology. In press.


Carstens, K., J. Anderson, P. Bachman, A. De Schrijver, G. Dively, B. Federici, M. Hamer, M. Gielkens, P. Jensen, W. Lamp, S. Rauschen, G. Ridley, J. Romeis, and A. Waggoner. 2011. Genetically modified crops and aquatic ecosystems: considerations for environmental risk assessment and non-target organism testing. Transgenic Research DOI: 10.1007/s11248-011-9569-8.


Lacey, L. A., D.F. Hoffman, and B. A. Federici. 2011. Histopathology and effect on development of the Phop GV on larvae of the potato tubermoth, Phthorimnea opercullea. Journal of Invertebrate Pathology 108: 52-55.


Swecicka, I., M. Sztchelsha, M. D. Czajkowska, D. K. Bideshi, and B. A. Federici. 2011. Characterization of Bacillus thuringiensis isolates from soil and small mammals that harbour vip3A gene homologues. Biocontrol Science and Technology 21, 461-473.


Federici, B. A., H.-W. Park, and D. K. Bideshi. 2010. Overview of the basic biology of Bacillus thuringiensis with emphasis on genetic engineering of bacterial larvicides for mosquito control. The Open Toxinology Journal 3, 154-171.


Wirth, M. C., W. E. Walton, and B. A. Federici. 2010. Inheritance patterns, dominance, stability, and allelism of insecticides resistance and cross-resistance in two colonies of Culex quinquefasciatus (Diptera: Culicidae) selected with Cry toxins from Bacillus thuringiensis susbp. israelensis. Journal of Medical Entomology 47, 814-822. PMID: 20939376.


Park, H.-W., D. K. Bideshi, and B. A. Federici. 2010. Properties and applied use of the mosquitocidal bacterium, Bacillus sphaericus. Journal of Asia-Pacific Entomology 13, 159-168.


Federici, B. A., and Y. Bigot. 2010. Evolution of immunosuppressive organelles from DNA viruses in insects. Chapter 14, pp. 229-248. In “Evolutionary Biology – Concepts, Molecular and Morphological Evolution,” (P. Pontarotti, Editor). Springer-Verlag Berlin, Heidelberg.


Wirth, M. C., W. E. Walton., and B. A. Federici. 2010. Evolution of resistance to the Bacillus sphaericus Bin toxin is phenotypically masked my combination with the mosquiotcidal proteins of Bacillus thuringiensis subspecies israelensis. Environmental Microbiology 12:1154-1160. PMID: 20141538.


Shelton, A. M., S. E. Naranjo., J. Romeis, R. L. Hellmich, J. D. Wolt, B. A. Federici, R. Albajes., F. Bigler, E. P. Burgess, G. P. Dively, A. M. Gatehouse, L. A. Malone, LR. Roush, M. Sears, F. Sehnal, N. Ferry, and H. A. Bell. 2009. Appropriate analytical methods are necessary to assess nontarget effects of insecticidal proteins in GM crops through meta-analysis (response to Andow et al. 2009). Environmental Entomology 38:1533-1538. PMID: 20021746.


Bigot, Y., S. Renault, J. Nicolas, C. Moundras, C., M. V. Demattei, S. Samain, D. K. Bideshi, and B. A. Federici. 2009. Symbiotic virus at the evolutionary intersection of three types of large DNA viruses; iridoviruses, ascoviruses, and ichnoviruses. PLoS One 4(7):e6397. PMID: 19636425.


Shelton, A. M., S. E. Naranjo., J. Romeis, R. L. Hellmich, J. D. Wolt, B. A. Federici, R. Albajes., F. Bigler, E. P. Burgess, G. P. Dively, A. M. Gatehouse, L. A. Malone, LR. Roush, M. Sears, and F. Sehnal. 2009. Setting the record straight: a rebuttal to an erroneous analysis on transgenic insecticidal crops and natural enemies. Transgenic Research 18:317-322. PMID: 19357987.


Shively, J. M., G. C. Cannon, S. Heinhorst, J. A. Fuerst, D. A. Bryant, E. Gantt, J. A. Maupin-Furlow, D. Schuler, F. Pfeifer, R. Docampo, C. Dahl, J. Preiss, A. Steinbuchel, and B. A. Federici. 2009. Intracellular structures of Prokaryotes: Inclusions, compartments, and assemblages, pp. 404-424. Encyclopedia of Microbiology. Elsevier Sciences, Amsterdam.


Sciocco, A. , D. K. Bideshi, J. J. Johnson, and B. A. Federici. 2009. Nuclear polyhedrosis virus of the western avocado leafroller, Amorbia cuneana: Isolation and characterization of a potential biological control agent. Biological Control 49, 154-159.


Tan, Y., T. Spears, D. K. Bideshi, R. Hice, Y. Bigot, and B. A. Federici. 2009. P64, a novel major virion structural protein is involved in condensing and packaging Spodoptera frugiperda ascovirus 1a genomic DNA. Journal of Virology 83, 2708-2714.


Park, H.-W., M. Tang, Y. Sakano, and B. A. Federici. 2009. Insertion of a 1.1 kb downstream region from Bacillus sphaericus 2362 into B. sphaericus 2297 decreases Bin toxin synthesis and mosquitocidal activity. Applied and Environmental Microbiology 75, 878-881.


Tan, Y., D. K. Bideshi, J. J. Johnson, Y. Bigot, and B. A. Federici. 2009. Proteomic analysis of the structural proteins in the Spodoptera frugiperda ascovirus 1avirion reveals 21 proteins. Journal of General Virology 90, 359-365.


Federici, B. A., Y. Bigot, D. K. Bideshi, Y. Tan, and T. Spears. 2009. Ascoviruses: superb manipulators of apoptosis for viral replication and dissemination. Current Topics in Microbiology and Immunology 328, 171-196.


Federici, B. A. 2009. Pathogens of Insects, pp. 757-765, In “Encyclopedia of Entomology” (V. H. Resh and R. T. Carde, Editors). Elsevier Sciences, Amsterdam.


Kapranis, A., B. A. Federici, R. F. Luck and J. J. Johnson. 2009. Cellular immune response of brown soft scale Coccus hesperidum L. (Hemiptera: Coccidae) to eggs of Metaphycus luteolus Timberlake (Hymenoptera: Encyrtidae). Biological Control 48, 1-5.


General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

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Dept of Entomology Information

417 Entomology Bldg.

Fax: (951) 827-3086
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